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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416050Generated: October 30, 2026

1-(5-(4-(Trifluoromethyl)phenyl)thiophen-2-yl)ethan-1-one → HCID 66624065, compound

https://huagongshe.com/reaction/416050

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(5-(4-(Trifluoromethyl)phenyl)thiophen-2-yl)ethan-1-oneHCID 4191494—
Reactant2,3-Difluoro-4-hydroxybenzaldehydeHCID 23107063—
ProductHCID 66624065HCID 66624065—

Reaction Steps

3-(2,3-Difluoro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one is prepared from 1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)ethanone and 2,3-difluoro-4-hydroxybenzaldehyde according to general procedure B. The evaporation residue is crystallized from acetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-4754c8fbb12749cd82a9b9168cfa9dbc
Source noteuspto-grants-2012_01