2,3-Dichloro-4-hydroxybenzaldehyde → 3-(2,3-Dichloro4-hydroxyphenyl)-1-(5-(4-(methylthio)phenyl)thien-2-yl)prop-2-en-1-one

HRID 416054Notes

Reaction equation

HRID 416054 reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[S:13][C:12]([C:14](=[O:16])[CH3:15])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[Cl:17][C:18]1[C:25]([Cl:26])=[C:24]([OH:27])[CH:23]=[CH:22][C:19]=1[CH:20]=O>>[Cl:17][C:18]1[C:25]([Cl:26])=[C:24]([OH:27])[CH:23]=[CH:22][C:19]=1[CH:20]=[CH:15][C:14]([C:12]1[S:13][C:9]([C:6]2[CH:7]=[CH:8][C:3]([S:2][CH3:1])=[CH:4][CH:5]=2)=[CH:10][CH:11]=1)=[O:16]

Participants

3

Reactant 2

HCID 5283802,3-Dichloro-4-hydroxybenzaldehydeHCID 4191496HCID 4191496, compound

Product 1

HCID 666239353-(2,3-Dichloro4-hydroxyphenyl)-1-(5-(4-(methylthio)phenyl)thien-2-yl)prop-2-en-1-one

Procedure

3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(4-(methylthio)phenyl)thien-2-yl)prop-2-en-1-one is prepared from 1-(5-(4-(methylthio)phenyl)thien-2-yl)ethanone and 2,3-dichloro-4-hydroxybenzaldehyde according to general procedure B. The evaporation residue is used “as is” for carrying out the next stage.

Sources & evidence

ORD record
ord-08fc7765066d4ba9b7e4c50dd7950c12
Source dataset
uspto-grants-2012_01
Patent number
US08088819B2

Reaction notes

Loading…