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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416059Generated: October 29, 2026

tert-Butyl 2-bromo-2-methylpropionate → Tert-butyl 2-(2,3-dichloro-4-(3-oxo-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)-2-methylpropanoate

https://huagongshe.com/reaction/416059

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 2-bromo-2-methylpropionateHCID 90290—
Reactant3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propan-1-oneHCID 59180355—
ProductTert-butyl 2-(2,3-dichloro-4-(3-oxo-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)-2-methylpropanoateHCID 25062864—

Reaction Steps

Tert-butyl 2-(2,3-dichloro-4-(3-oxo-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)-2-methylpropanoate is prepared from 3-(2,3-dichloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propan-1-one and tert-butyl bromoisobutyrate according to general procedure D.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-ca31d9fa1b5746939e5003b677d00c48
Source noteuspto-grants-2012_01