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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416064Generated: October 30, 2026

tert-Butyl 2-bromobutanoate → Tert-butyl 2-(2,3-dichloro-4-(3-oxo-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)butanoate

https://huagongshe.com/reaction/416064

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 2-bromobutanoateHCID 13124118—
Reactant3-(2,3-Dichloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propan-1-oneHCID 59180355—
ProductTert-butyl 2-(2,3-dichloro-4-(3-oxo-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)butanoateHCID 25063128—

Reaction Steps

Tert-butyl 2-(2,3-dichloro-4-(3-oxo-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)-butanoate is prepared from 3-(2,3-dichloro-4-hydroxyphenyl)-1-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propan-1-one and tert-butyl 2-bromobutanoate according to general procedure D.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-884b4be70f9d47fc82791fe60d0e61c5
Source noteuspto-grants-2012_01