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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416090Generated: October 30, 2026

Methyl iodide → HCID 25060769, compound

https://huagongshe.com/reaction/416090

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium hydrideHCID 24758—
ReactantHCID 25062866HCID 25062866—
ProductHCID 25060769HCID 25060769—

Reaction Steps

2-(2,3-Dichloro-4-(3-methoxy-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)-propyl)phenoxy)-2-methylpropanoic acid is prepared from 2-(2,3-dichloro-4-(3-hydroxy-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)-2-methylpropanoic acid using 2.2 equivalents of sodium hydride and 2.2 equivalents of iodomethane according to general procedure H.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-5ffc114a8c95459cb529102f4a617ba9
Source noteuspto-grants-2012_01