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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416092Generated: October 29, 2026

Sodium hydride → HCID 25060770, compound

https://huagongshe.com/reaction/416092

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
ReactantCyclohexane, (bromomethyl)-HCID 137636—
ReactantHCID 25062866HCID 25062866—
ProductHCID 25060770HCID 25060770—

Reaction Steps

2-(2,3-Dichloro-4-(3-(cyclohexylmethoxy)-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)-2-methylpropanoic acid is prepared from 2-(2,3-dichloro-4-(3-hydroxy-3-(5-(4-(trifluoromethyl)phenyl)thien-2-yl)propyl)phenoxy)-2-methylpropanoic acid using 8 equivalents of sodium hydride and 2.5 equivalents of bromomethylcyclohexane according to general procedure H.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-fa542a982e1e4b3980c212aae645d092
Source noteuspto-grants-2012_01