Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416102Generated: October 30, 2026

Trifluoroacetic acid → 2-(4-(3-(5-(4-Bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoic acid

https://huagongshe.com/reaction/416102

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantTert-butyl 2-(4-(3-(5-(4-bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoateHCID 25061023—
Product2-(4-(3-(5-(4-Bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoic acidHCID 25061024—

Reaction Steps

2-(4-(3-(5-(4-Bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoic acid is prepared from tert-butyl 2-(4-(3-(5-(4-bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoate according to general procedure E using 38 equivalents of trifluoroacetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-4ac46c4292364579ae6b3616fb05ed57
Source noteuspto-grants-2012_01