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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 416118Generated: October 31, 2026

Methyl iodide → HCID 59180317, compound

https://huagongshe.com/reaction/416118

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium hydrideHCID 24758—
ReactantHCID 59180327HCID 59180327—
ProductHCID 59180317HCID 59180317—

Reaction Steps

2-(2,3-Dichloro-4-(3-methoxy-3-(5-(4-(trifluoromethoxy)phenyl)thien-2-yl)-propyl)phenoxy)-2-methylpropanoic acid is prepared from 2-(2,3-dichloro-4-(3-hydroxy-3-(5-(4-(trifluoromethoxy)phenyl)thien-2-yl)propyl)phenoxy)-2-methylpropanoic acid using 2.1 equivalents of sodium hydride and 2.1 equivalents of iodomethane according to general procedure H.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08088819B2
Source datasetuspto-grants-2012_01
ORD IDord-60f90bcf00d74a98adb3819bebefd910
Source noteuspto-grants-2012_01