HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetylpyrazine → 4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)-N-(2-aminophenyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetylpyrazine | HCID 30914 | — |
| Reactant | 1-(1H-pyrazol-3-yl)ethan-1-one | HCID 333471 | — |
| Reactant | N-(2-aminophenyl)-4-((4-(pyrazin-2-yl)pyrimidin-2-ylamino)methyl)benzamide | HCID 44570891 | — |
| Product | 4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)-N-(2-aminophenyl)benzamide | HCID 25195084 | — |
Reaction Steps
Title compound was obtained according to the scheme 6 similarly to the compound 26a (Example 29) using instead of 1-pyrazin-2-yl-ethanone as the starting material 1-(2H-pyrazol-3-yl)-ethanone (Table 11). Characterization of the title compound is provided in the Table 12.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088805B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-006aa4a1013c4723905c098b855d4c77 |
| Source note | uspto-grants-2012_01 |