Acetylpyrazine → N-(2-Amino-phenyl)-4-{[4-(2,4-dimethyl-oxazol-5-yl)-pyrimidin-2-ylamino]-methyl}-benzamide

Participants

Role	Name	HCID	Charge
Reactant	Acetylpyrazine	HCID 30914	—
Reactant	5-Acetyl-2,4-dimethyloxazole	HCID 318418	—
Reactant	N-(2-aminophenyl)-4-((4-(pyrazin-2-yl)pyrimidin-2-ylamino)methyl)benzamide	HCID 44570891	—
Product	N-(2-Amino-phenyl)-4-{[4-(2,4-dimethyl-oxazol-5-yl)-pyrimidin-2-ylamino]-methyl}-benzamide	HCID 11683076	—

Reaction Steps

Title compound was obtained according to the scheme 6 similarly to the compound 26a (Example 29) using instead of 1-pyrazin-2-yl-ethanone as the starting material 1-(2,4-dimethyl-oxazol-5-yl)-ethanone (Table 11). Characterization of the title compound is provided in the Table 12.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08088805B2
Source dataset	uspto-grants-2012_01
ORD ID	ord-52ed4a6d33304bce82333e21419f7f96
Source note	uspto-grants-2012_01