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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 416277생성일: 2026년 10월 25일

Acetylpyrazine → N-(2-aminophenyl)-4-((4-(3-(hydroxymethyl)-5-methylisoxazol-4-yl)pyrimidin-2-ylamino)methyl)benzamide

https://huagongshe.com/reaction/416277

반응식

참여 물질

역할이름HCID투입량
반응물AcetylpyrazineHCID 30914—
반응물N-(2-aminophenyl)-4-((4-(pyrazin-2-yl)pyrimidin-2-ylamino)methyl)benzamideHCID 44570891—
반응물1-(3-(Hydroxymethyl)-5-methylisoxazol-4-yl)ethanoneHCID 45117985—
생성물N-(2-aminophenyl)-4-((4-(3-(hydroxymethyl)-5-methylisoxazol-4-yl)pyrimidin-2-ylamino)methyl)benzamideHCID 58930487—

반응 단계

Title compound was obtained according to the scheme 6 similarly to the compound 26a (Example 29) using instead of 1-pyrazin-2-yl-ethanone as the starting material the ketone 324 (Table 11). Characterization of the title compound is provided in the Table 12.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08088805B2
출처 데이터셋uspto-grants-2012_01
ORD IDord-5f9bc62516ea402a9d86db80117b19a6
출처 메모uspto-grants-2012_01