4-[5-(4-Chloro-phenyl)-2-ethyl-thiophen-3-yl]-10-oxa-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione → HCID 68775349, compound

Participants

Reaction Steps

A solution of 4-[5-(4-chloro-phenyl)-2-ethyl-thiophen-3-yl]-10-oxa-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione (180 mg, 0.47 mmol) in methanol (5 ml) is stirred under hydrogen (3 bars) for 7 hours. The reaction solution is filtered through a Celite pad and the filtrate concentrated to give 4-[5-(4-chloro-phenyl)-2-ethyl-thiophen-3-yl]-10-oxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione (51 mg).

Provenance & Evidence