Sodium Hydroxide → HCID 46928680, compound

Participants

Reaction Steps

A similar procedure as described in Example 43, step 5 was used, starting from 4-[3-[6-(5-ethoxy-biphenyl-3-yloxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (240 mg, 0.4 mmol) and 1.0 N aqueous sodium hydroxide (4 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-(5-ethoxy-biphenyl-3-yloxy)-hexyl]-phenoxy]-butyric acid (210 mg, 96%) as a light brown waxy solid: ES(+)-HRMS m/e calcd for C33H40O7 (M+Na)+ 571.2666. found 571.2665.

Provenance & Evidence