Sodium Hydroxide → HCID 46928682, compound

Participants

Reaction Steps

A similar procedure as described in Example 43, step 5 was used, starting from 4-[3-{6-[3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-ethoxy-phenoxy]-hexyl}-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (70 mg, 0.1 mmol) and 1.0 N aqueous sodium hydroxide (1 mL) to afford 4-[2-(2-carboxy-ethyl)-3-{6-[3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-ethoxy-phenoxy]-hexyl}-phenoxy]-butyric acid (62 mg, 99%) as a light brown waxy solid: ES(+)-HRMS m/e calcd for C35H42O9 (M+Na)+ 629.2721. found 629.2721.

Provenance & Evidence