Sodium Hydroxide → HCID 46928683, compound

Participants

Reaction Steps

A similar procedure as described in Example 43, step 5 was used, starting from 4-[2-(2-ethoxycarbonyl-ethyl)-3-[6-(5-ethoxy-3′-fluoro-biphenyl-3-yloxy)-hexyl]-phenoxy]-butyric acid ethyl ester (210 mg, 0.34 mmol) and 1.0 N aqueous sodium hydroxide (3.4 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-(5-ethoxy-3′-fluoro-biphenyl-3-yloxy)-hexyl]-phenoxy]-butyric acid (190 mg, 99%) as a light brown waxy solid: ES(+)-HRMS m/e calcd for C33H39FO7 (M+Na)+ 589.2572. found 589.2573.

Provenance & Evidence