Sodium Hydroxide → HCID 46928781, compound

Participants

Reaction Steps

A similar procedure as described in Example 43, step 5 was used, starting from 4-[2-(2-ethoxycarbonyl-ethyl)-3-[6-(5-ethoxy-4′-methanesulfonyl-biphenyl-3-yloxy)-hexyl]-phenoxy]-butyric acid ethyl ester (52 mg, 0.076 mmol) and 1.0 N aqueous sodium hydroxide (1.0 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-(5-ethoxy-4′-methanesulfonyl-biphenyl-3-yloxy)-hexyl]-phenoxy]-butyric acid (44 mg, 91%) as a light brown solid: ES(+)-HRMS m/e calcd for C34H42O9S (M+Na)+ 649.2442. found 649.2442.

Provenance & Evidence