HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 46928782, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 59496842 | HCID 59496842 | — |
| Product | HCID 46928782 | HCID 46928782 | 98.4% |
Reaction Steps
A similar procedure as described in Example 43, step 5 was used, starting from 4-[3-{6-[3-(2-chloro-pyridin-4-yl)-5-ethoxy-phenoxy]-hexyl}-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (105 mg, 0.16 mmol) and 1.0 N aqueous sodium hydroxide (1.6 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-[3-(2-chloro-pyridin-4-yl)-5-ethoxy-phenoxy]-hexyl]-phenoxy]-butyric acid (92 mg, 96%) as a light brown solid: ES(+)-HRMS m/e calcd for C32H38ClNO7 (M+H)+ 584.2410. found 584.2412.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088936B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-2e76574f035a4a09b85970b911985778 |
| Source note | uspto-grants-2012_01 |