Sodium Hydroxide → HCID 46928985, compound

Participants

Reaction Steps

A similar procedure as described in Example 43, step 5 was used, starting from 4-[3-[6-(5-benzyloxy-3′-fluoro-biphenyl-3-yloxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (229 mg, 0.34 mmol) and 1.0 N aqueous sodium hydroxide (5 mL) to afford 4-[3-[6-(5-benzyloxy-3′-fluoro-biphenyl-3-yloxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy]-butyric acid (163 mg, 78%) as an amorphous white solid: ES(+)-HRMS m/e calcd for C38H41FO7 (M+Na)+ 651.2728. found 651.2729.

Provenance & Evidence