Sodium Hydroxide → HCID 46928986, compound

Participants

Reaction Steps

A similar procedure as described in Example 43, step 5 was used, starting from 4-[3-[6-(3-benzo[1,3]dioxol-5-yl-5-benzyloxy-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (254 mg, 0.36 mmol) and 1.0 N aqueous sodium hydroxide (5 mL) to afford 4-[3-[6-(3-benzo[1,3]dioxol-5-yl-5-benzyloxy-phenoxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy]-butyric acid (107 mg, 46%) as an amorphous off-white solid: ES(+)-HRMS m/e calcd for C39H42O9 (M+Na)+ 677.2721. found 677.2718.

Provenance & Evidence