Sodium Hydroxide → HCID 46929077, compound

Participants

Reaction Steps

A similar procedure as described in Example 43, step 5 was used, starting from 4-[3-[6-(3-cyclopentylmethoxy-5-thiophen-3-yl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (117 mg, 0.17 mmol) and 1.0 N aqueous sodium hydroxide (5 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-(3-cyclopentylmethoxy-5-thiophen-3-yl-phenoxy)-hexyl]-phenoxy]-butyric acid (104 mg, 98%) as a off-white waxy solid: ES(+)-HRMS m/e calcd for C35H44O7S (M+H)+ 609.2881. found 609.2881.

Provenance & Evidence