HuagongsheHuagongshe Chemistry Print Report · For research reference only
Di-tert-butyl azodicarboxylate → HCID 66619288, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Di-tert-butyl azodicarboxylate | HCID 97268 | — |
| Reactant | 2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-ethanol | HCID 66619310 | — |
| Reactant | HCID 178498597 | HCID 178498597 | — |
| Product | HCID 66619288 | HCID 66619288 | — |
Reaction Steps
The title compound was prepared in analogy to Example 4, intermediate, from 2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-ethanol (Ex. 1, int. c) and 2-hydroxy-6-methoxy-isonicotinic acid methyl ester (commercially available) and replacing di-ethyl azodicarboxylate by di-tert-butyl azodicarboxylate. Light yellow oil (77%). MS (Turbo Spray): m/z=556.2 [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08088930B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-b00fe09e0c6d4e28a5de465c996812dc |
| Source note | uspto-grants-2012_01 |