反应详情

Step C A suspension of 2-methoxy-4-(3-(methylsulfonyl)propoxy)-1-nitrobenzene (0.4 g, 1.6 mmol) and Pd/C (Aldrich, 10%, 0.1 g) in methanol (15 mL) was vigorously shaken in a Parr under atmosphere of H2 (50 psi) for 0.5 h. The mixture was filtered through a short pad of celite. The filtrate was concentrated to give 4-(3-methanesulfonyl-propoxy)-2-methoxy-phenylamine as a black oil (0.48 g, 92%).

1. filtrationThe mixture was filtered through a short pad of celite
2. concentrationThe filtrate was concentrated