HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Hydroxypiperidin-1-yl)benzaldehyde → HCID 178516623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Hydroxypiperidin-1-yl)benzaldehyde | HCID 12717446 | — |
| Reactant | Tert-butyl malonate | HCID 21883978 | — |
| Reactant | Sodium t-butoxide | HCID 23676156 | — |
| Reactant | 1-Isocyano-2-methylpropan-2-yl methyl carbonate | HCID 25267464 | — |
| Reactant | HCID 178507353 | HCID 178507353 | — |
| Product | HCID 178516623 | HCID 178516623 | — |
Reaction Steps
The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (0.970 g, 7.3 mmol), 4-(4-hydroxypiperidin-1-yl)benzaldehyde (1.5 g, 7.3 mmol), mono-tert-butyl malonate (1.17 g, 7.3 mmol), 1-isocyano-2-methylpropan-2-yl methyl carbonate (1.15 g, 7.3 mmol) and sodium tert.-butoxide (1.5 g, 14.6 mmol) according to method 5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08530670B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-84d2db6385904b519ccf9fce77940e80 |
| Source note | uspto-grants-2013_09 |