Cyclohexylamine → HCID 178516390, compound

HRID 41772Notes

Reaction equation

HRID 41772 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[C:19]([F:21])[CH:18]=[C:17]([F:22])[C:16]=4[F:23])[C:13](O)=[CH:12][C:11]3=[O:25])=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH:26]1([NH2:32])[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[C:19]([F:21])[CH:18]=[C:17]([F:22])[C:16]=4[F:23])[C:13]([NH:32][CH:26]4[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]4)=[CH:12][C:11]3=[O:25])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 7965CyclohexylamineHCID 178516576HCID 178516576, compound

Product 1

HCID 178516390HCID 178516390, compound

Procedure

The compound was synthesized starting from 1-(1H-benzo[d]imidazol-5-yl)-4-hydroxy-5-(2,3,5-trifluorophenyl)-1H-pyrrol-2(5H)-one (0.115 g, 0.3 mmol) and cyclohexylamine (0.48 ml, 4.2 mmol) according to method 7 described above.

Workup

  1. customThe compound was synthesized

Sources & evidence

ORD record
ord-ccecdbbe05364915ba306aef5f528b51
Source dataset
uspto-grants-2013_09
Patent number
US08530670B2

Reaction notes

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