Cyclohexylamine → HCID 178516388, compound

HRID 41773Notes

Reaction equation

[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[CH:19][CH:18]=[C:17]([F:21])[C:16]=4[F:22])[C:13](O)=[CH:12][C:11]3=[O:24])=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH:25]1([NH2:31])[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]([C:15]4[CH:20]=[CH:19][CH:18]=[C:17]([F:21])[C:16]=4[F:22])[C:13]([NH:31][CH:25]4[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]4)=[CH:12][C:11]3=[O:24])=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

Reactant 2

HCID 7965Cyclohexylamine

HCID 178516571HCID 178516571, compound

Product 1

HCID 178516388HCID 178516388, compound

Procedure

The compound was synthesized starting from 1-(1H-benzo[d]imidazol-5-yl)-5-(2,3-difluorophenyl)-4-hydroxy-1H-pyrrol-2(5H)-one (0.12 g, 0.33 mmol) and cyclohexylamine (0.53 ml 4.62 mmol) according to method 7 described above.

Workup

customThe compound was synthesized

Sources & evidence

ORD record: ord-6a0b03448f684e689603a8d7327a442e
Source dataset: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08530670B2

Reaction notes

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