Chloroform → HCID 86638315, compound

Participants

Reaction Conditions

Reaction Steps

2,4,6-Trihydroxybenzaldehyde (435 mg, 2.53 mmol), 1-bromohexadecane (4.58 g, 15.0 mmol), K2CO3 (1.04 g, 4.52 mmol) and KI (70 mg, 0.42 mmol) were mixed in DMF (15 ml), followed by stirring at 70° C. for 20 hours. The resulting reaction product was cooled to 20° C., and chloroform (100 ml) was added thereto to separate into an organic phase and an aqueous phase. The subsequent operations are the same as in Example 1, and therefore are omitted to describe. Thus, white solid 2,4,6-trihexadecyloxybenzaldehyde (2a) was obtained (1.04 g, yield: 50%). It was confirmed by 1H NMR quantitative analysis that 2a is 2,4,6-trihexadecyloxybenzaldehyde.

Provenance & Evidence