7460-12-0 → Pseudoephedrine

HRID 417762Notes

Reaction equation

HRID 417762 reaction equation
[CH3:1][C@H:2]([NH:11][CH3:12])[C@@H:3]([OH:10])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1.OS(O)(=O)=O>O>[CH3:1][C@H:2]([NH:11][CH3:12])[C@@H:3]([OH:10])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 1

HCID 629457460-12-0

Product 1

HCID 7028Pseudoephedrine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

The hydroxypropyl cellulose and polyethylene glycol were added into 16.5 kg of purified water and stirred until a clear solution was obtained. The pseudoephedrine sulfate was added to the solution using a homogenizer and allowed to fully dissolve. The talc was then mixed into the solution using a homogenizer. 0.45 kg of purified water was used to rinse the container holding the polyethylene glycol and the homogenizer. The rinse material was added to the coating solution. A mechanical stirrer was used to stir the coating suspension until it was completely consumed by the coating process.

Workup

  1. customwas obtained
  2. dissolutionto fully dissolve
  3. washto rinse the container
  4. additionThe rinse material was added to the coating solution
  5. customA mechanical stirrer was used
  6. stirringto stir the coating suspension until it
  7. customwas completely consumed by the coating process

Sources & evidence

ORD record
ord-e0b5e298025d4d9a9b9ca64974691da8
Source dataset
uspto-grants-2012_01
Patent number
US08092831B2

Reaction notes

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