HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 178516340, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4,4-Difluoropiperidine hydrochloride | HCID 2758351 | — |
| Reactant | HCID 178516575 | HCID 178516575 | — |
| Solvent | Dimethylformamide toluene | HCID 21735183 | — |
| Product | HCID 178516340 | HCID 178516340 | — |
Reaction Steps
The compound was synthesized starting from 1-(1H-benzo[d]imidazol-5-yl)-4-hydroxy-5-(4-morpholinophenyl)-1H-pyrrol-2(5H)-one (1.0 g, 2.65 mmol), 4,4-difluoropiperidine hydrochloride (0.800 g, 5.1 mmol) and K2CO3 (0.73 g, 5.3 mmol) in toluene/DMF (2:1; 15 ml) according to method 8a described above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08530670B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-7083fea5a4464f51be27cf64c9566bdf |
| Source note | uspto-grants-2013_09 |