Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Chloro-2-nitroaniline → 5-Methoxy-2-nitroaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Chloro-2-nitroaniline | HCID 74218 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-Methoxy-2-nitroaniline | HCID 85300 | 93.9% |
반응 단계
10 g of 5-chloro-2-nitroaniline are dissolved in 100 ml of methanol, and 32.3 g of sodium methoxide are added. The reaction mixture is heated at the boil under reflux for 18 hours. After cooling, the mixture is evaporated to dryness, 500 ml of water are added, and the crude product is isolated by filtration. Drying gives 9.15 g of 5-methoxy-2-nitroaniline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08093240B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-e21e12bcfccb420281768b7ca8abdaf5 |
| 출처 메모 | uspto-grants-2012_01 |