HuagongsheHuagongshe Chemistry Print Report · For research reference only
Di-tert-butyl dicarbonate → tert-butyl N-(prop-2-yn-1-yl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Di-tert-butyl dicarbonate | HCID 90495 | — |
| Reactant | Propargylamine | HCID 239041 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | tert-butyl N-(prop-2-yn-1-yl)carbamate | HCID 11073648 | — |
Reaction Steps
A solution of propargylamine (1 g, 18 mmol) in DCM (10 mL) was treated with (BOC)2O (4.0 g, 18 mmol) at rt for 3 h. Evaporation gave the title compound as an oil. 1H NMR (CDCl3) δ 4.80 (s, 1H), 3.93 (s, 2H), 2.23 (t, 1H), 1.47 (s, 9H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093229B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-6ad678f0f6354a0e864d4f5db7c8bcfd |
| Source note | uspto-grants-2012_01 |