HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-Butylamine → Tert-butyl-pent-4-ynyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | 5-Iodo-1-pentyne | HCID 11019720 | — |
| Product | Tert-butyl-pent-4-ynyl-amine | HCID 57713825 | — |
Reaction Steps
A solution of 5-iodo-pent-1-yne (1.0 g, 5.2 mmol) in tert-BuNH2 (2.0 g. 27 mmol) was heated to reflux for 4 h, evaporated, diluted with Et2O, filtered, and concentrated to afford the title compound. 1H NMR (CDCl3) δ 2.67 (t, 2H), 2.27 (td, 2H), 1.96 (t, 1H), 1.70 (quint., 2H), 1.11 (s, 9H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093229B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-278f103381b04ae7aaf078b768d5199a |
| Source note | uspto-grants-2012_01 |