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HRID417860

反应详情

EQUATION

反应方程式

HRID 417860 的结构方程式

REACTANTS

反应物

2
结构：C#CCCCN1CCN(C)CC1
HCID23446116

1-Methyl-4-(4-pentyn-1-yl)piperazine

C10H18N2

结构：COc1c(C)cnc(Cn2cc(I)c3c(Cl)nc(N)nc32)c1C
HCID44228964

4-Chloro-5-iodo-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine

C15H15ClIN5O

PRODUCTS

生成物

1
结构：COc1c(C)cnc(Cn2cc(C#CCCCN3CCN(C)CC3)c3c(Cl)nc(N)nc32)c1C
HCID57713835

未命名化合物

PROCEDURE

实验过程

Sonogashira coupling of 4-chloro-5-iodo-7-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7H-pyrrolo [2,3-d]pyrimidin-2-amine with 1-methyl-4-(pent-4-ynyl)piperazine, according to the general procedure A gave the title compound, as a solid. Mp=160.1-162.3° C. HPLC Rt=4.08 min.