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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 418089Generated: October 29, 2026

Sodium Hydroxide → HCID 178504819, compound

https://huagongshe.com/reaction/418089

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 178471690HCID 178471690—
ProductHCID 178504819HCID 17850481983.8%

Reaction Steps

A similar procedure as described in Example 40, step 8 was used, starting from 4-(2-(2-ethoxycarbonyl-ethyl)-3-{6-[3-methanesulfonyl-5-(1H-pyrazol-3-yl)-phenoxy]-hexyl}-phenoxy)-butyric acid ethyl ester (35 mg, 0.05 mmol) and 1.0 N aqueous sodium hydroxide (0.4 mL) to afford 4-(2-(2-carboxy-ethyl)-3-{6-[3-methanesulfonyl-5-(1H-pyrazol-3-yl)-phenoxy]-hexyl}-phenoxy)-butyric acid (24 mg, 75%) as an amorphous white solid: ES(+)-HRMS m/e calcd for C29H36N2O8S (M+Na)+ 595.2084, found 595.2080.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093253B2
Source datasetuspto-grants-2012_01
ORD IDord-b1b1ecfd16a245e4a2ca732f4b48185f
Source noteuspto-grants-2012_01