HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178504819, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178471690 | HCID 178471690 | — |
| Product | HCID 178504819 | HCID 178504819 | 83.8% |
Reaction Steps
A similar procedure as described in Example 40, step 8 was used, starting from 4-(2-(2-ethoxycarbonyl-ethyl)-3-{6-[3-methanesulfonyl-5-(1H-pyrazol-3-yl)-phenoxy]-hexyl}-phenoxy)-butyric acid ethyl ester (35 mg, 0.05 mmol) and 1.0 N aqueous sodium hydroxide (0.4 mL) to afford 4-(2-(2-carboxy-ethyl)-3-{6-[3-methanesulfonyl-5-(1H-pyrazol-3-yl)-phenoxy]-hexyl}-phenoxy)-butyric acid (24 mg, 75%) as an amorphous white solid: ES(+)-HRMS m/e calcd for C29H36N2O8S (M+Na)+ 595.2084, found 595.2080.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093253B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-b1b1ecfd16a245e4a2ca732f4b48185f |
| Source note | uspto-grants-2012_01 |