Sodium Hydroxide → HCID 44219162, compound

Participants

Reaction Steps

A similar procedure as described in Example 40, step 8 was used, starting from 4-[2-(2-ethoxycarbonyl-ethyl)-3-[6-(5-(propane-1-sulfonyl)-4′-fluoro-biphenyl-3-yloxy)-hexyl]-phenoxy]-butyric acid ethyl ester (195 mg, 0.29 mmol) and 1.0 N aqueous sodium hydroxide (2.9 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-(5-(propane-1-sulfonyl)-4′-fluoro-biphenyl-3-yloxy)-hexyl]-phenoxy]-butyric acid (156 mg, 87%) as an amorphous white solid: ES(+)-HRMS m/e calcd for C34H41FO8S (M+Na)+ 651.2398, found 651.2398.

Provenance & Evidence