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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 418126Generated: October 30, 2026

Sodium Hydroxide → HCID 57863098, compound

https://huagongshe.com/reaction/418126

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 57863115HCID 57863115—
ProductHCID 57863098HCID 5786309892.6%

Reaction Steps

A similar procedure as described in Example 40, step 8 was used, starting from 4-[2-(2-ethoxycarbonyl-ethyl)-3-[6-(3-(propane-1-sulfonyl)-5-thiophen-3-yl-phenoxy)-hexyl]-phenoxy]-butyric acid ethyl ester (144 mg, 0.21 mmol) and 1.0 N aqueous sodium hydroxide (2.1 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-(3-(propane-1-sulfonyl)-5-thiophen-3-yl-phenoxy)-hexyl]-phenoxy]-butyric acid (120 mg, 91%) as an amorphous white solid: ES(+)-HRMS m/e calcd for C32H40O8S2 (M+Na)+ 639.2057, found 639.2056.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093253B2
Source datasetuspto-grants-2012_01
ORD IDord-27b6c7b5ffc046b6bfdb01d9bedbf7a5
Source noteuspto-grants-2012_01