HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 57863098, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 57863115 | HCID 57863115 | — |
| Product | HCID 57863098 | HCID 57863098 | 92.6% |
Reaction Steps
A similar procedure as described in Example 40, step 8 was used, starting from 4-[2-(2-ethoxycarbonyl-ethyl)-3-[6-(3-(propane-1-sulfonyl)-5-thiophen-3-yl-phenoxy)-hexyl]-phenoxy]-butyric acid ethyl ester (144 mg, 0.21 mmol) and 1.0 N aqueous sodium hydroxide (2.1 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-(3-(propane-1-sulfonyl)-5-thiophen-3-yl-phenoxy)-hexyl]-phenoxy]-butyric acid (120 mg, 91%) as an amorphous white solid: ES(+)-HRMS m/e calcd for C32H40O8S2 (M+Na)+ 639.2057, found 639.2056.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093253B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-27b6c7b5ffc046b6bfdb01d9bedbf7a5 |
| Source note | uspto-grants-2012_01 |