Sodium Hydroxide → HCID 57863045, compound

Participants

Reaction Steps

A similar procedure as described in Example 40, step 8 was used, starting from 4-[2-(2-ethoxycarbonyl-ethyl)-3-[6-(5-(propane-2-sulfonyl)-4′-chloro-biphenyl-3-yloxy)-hexyl]-phenoxy]-butyric acid ethyl ester (132 mg, 0.18 mmol) and 1.0 N aqueous sodium hydroxide (1.8 mL) to afford 4-[2-(2-carboxy-ethyl)-3-[6-(5-(propane-2-sulfonyl)-4′-chloro-biphenyl-3-yloxy)-hexyl]-phenoxy]-butyric acid (57 mg, 47%) as an amorphous white solid: ES(+)-HRMS m/e calcd for C34H41ClO8S (M+Na)+ 667.2103, found 667.2101.

Provenance & Evidence