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HRID418189

反应详情

EQUATION

反应方程式

HRID 418189 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(Cl)cc3)nc12
HCID53212223

未命名化合物

结构：N=C(NO)c1ccc(S(N)(=O)=O)cc1
HCID178513360

未命名化合物

PRODUCTS

生成物

1
结构：NS(=O)(=O)c1ccc(-c2noc(-c3cnn4c(C(F)(F)F)cc(-c5ccc(Cl)cc5)nc34)n2)cc1
HCID16068769

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 5-(4-chloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.4) (171 mg, 0.5 mmol) and N-hydroxy-4-sulfamoyl-benzamidine [CAS-No. 4476-10-2] (161 mg, 0.75 mmol) according to general procedure II. Obtained after purification by flash chromatography (ethyl acetate/heptane) and crystallization (dichloromethane) as a yellow solid (150 mg, 58%). MS (EI) 520.0 [(M)+]; mp 296° C.

WORKUP

后处理

  1. customObtained
  2. customafter purification
  3. customby flash chromatography (ethyl acetate/heptane) and crystallization (dichloromethane) as a yellow solid (150 mg, 58%)