Hydrochloric Acid → HCID 59190788, compound

Participants

Reaction Steps

Dissolved 3-{3-[(3,4-dimethoxy-benzoylamino)-methyl]-benzoylamino}-7,8-dihydro-5H-[1,6]naphthyridine-6-carboxylic acid tert-butyl ester (120 mg, 0.22 mmol) in 3 mL CH2Cl2 and added HCl in dioxane (1.00 mL/4.0 mmol). The mixture was stirred overnight resulting in a heterogenous mixture. Concentrated the mixture to dryness to give 100.7 mg of the desired product. MS, electrospray 447.4 (M+H).

Provenance & Evidence