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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 418365Generated: October 29, 2026

Water → 2-Methoxy-5-tetrazol-1-yl-benzaldehyde

https://huagongshe.com/reaction/418365

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantMethyl iodideHCID 6328—
ReactantPotassium CarbonateHCID 11430—
Reactant2-Hydroxy-5-tetrazol-1-yl-benzaldehydeHCID 10845344—
SolventDimethylformamideHCID 6228—
Product2-Methoxy-5-tetrazol-1-yl-benzaldehydeHCID 1053616967%

Reaction Steps

To a solution of 2-hydroxy-5-tetrazol-1-yl-benzaldehyde (2.63 mmol) in dimethylformamide (5 ml) was added potassium carbonate (3.95 mmol) and iodomethane (3.95 mmol) and the mixture was stirred under nitrogen atmosphere for 2 h. The mixture was poured into water (100 ml) and the white solid formed filtered to afford the title compound in a 67% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093268B2
Source datasetuspto-grants-2012_01
ORD IDord-bea2fe5fffd6405ab643b1222ac4cf15
Source noteuspto-grants-2012_01