HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Methoxy-5-tetrazol-1-yl-benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Hydroxy-5-tetrazol-1-yl-benzaldehyde | HCID 10845344 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Methoxy-5-tetrazol-1-yl-benzaldehyde | HCID 10536169 | 67% |
Reaction Steps
To a solution of 2-hydroxy-5-tetrazol-1-yl-benzaldehyde (2.63 mmol) in dimethylformamide (5 ml) was added potassium carbonate (3.95 mmol) and iodomethane (3.95 mmol) and the mixture was stirred under nitrogen atmosphere for 2 h. The mixture was poured into water (100 ml) and the white solid formed filtered to afford the title compound in a 67% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093268B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-bea2fe5fffd6405ab643b1222ac4cf15 |
| Source note | uspto-grants-2012_01 |