4-Chloro-7-(trifluoromethyl)quinoline → HCID 131729348, compound

HRID 418434Notes

Reaction equation

HRID 418434 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([CH3:11])=[CH:6][CH:5]=2.[Cl:12][C:13]1[C:22]2[C:17](=[CH:18][C:19]([C:23]([F:26])([F:25])[F:24])=[CH:20][CH:21]=2)[N:16]=[CH:15][CH:14]=1>>[ClH:12].[CH3:1][C:2]1[NH:3][C:4]2[C:9]([C:10]=1[C:13]1[C:22]3[C:17](=[CH:18][C:19]([C:23]([F:26])([F:24])[F:25])=[CH:20][CH:21]=3)[N:16]=[CH:15][CH:14]=1)=[CH:8][C:7]([CH3:11])=[CH:6][CH:5]=2

Participants

3

Reactant 2

HCID 676684-Chloro-7-(trifluoromethyl)quinolineHCID 709652,5-Dimethyl-1H-indole

Product 1

HCID 131729348HCID 131729348, compound

Procedure

The sub-title compound was prepared by the method of Example 15 step, a, using 2,5-dimethylindole and 4-chloro-7-trifluoromethylquinoline.

Sources & evidence

ORD record
ord-930b6d694cf343a7baa43ecec201a60f
Source dataset
uspto-grants-2012_01
Patent number
US08093278B2

Reaction notes

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