反应详情

温度

45 °C

A mixture of (R)-6-chloro-2-(1-hydroxypropan-2-yl)-5-nitroisoquinolin-1 (2H)-one (2H)-one 750.0 mg, 0.002653 mol), acetic anhydride (0.325 mL, 0.00345 mol), pyridine (0.322 mL, 0.00398 mol) and methylene chloride (20 mL, 0.3 mol) was heated at 45° C. over night. The solvents were removed under reduced pressure and dried to afford the product as a thick yellow oil.

1. customThe solvents were removed under reduced pressure
2. customdried