反应详情

A mixture of (R)-2-(1-hydroxypropan-2-yl)-6-methyl-5-nitroisoquinolin-1-(2H)-one (100.0 mg, 0.0003813 mol), pyridine (0.062 mL, 0.00076 mol), acetic anhydride (0.0432 mL, 0.000458 mol) and methylene chloride (5 mL, 0.08 mol) was stirred at room temperature overnight. The solvent was removed under reduced pressure, and the resulting product was dried under vacuum (yellow oil) and was used in the next step without any purification.

1. customThe solvent was removed under reduced pressure
2. customthe resulting product was dried under vacuum (yellow oil)
3. customwas used in the next step without any purification