Methanol → HCID 25014315, compound

Participants

Reaction Steps

A mixture of (R)-2-(6-chloro-5-((1-hydroxy-4-(trifluoromethyl)cyclohexyl)methylcarbamoyl)-1-oxoisoquinolin-2(1H)-yl)propyl acetate (76 mg, 0.00014 mol) and potassium carbonate (20 mg, 0.0001 mol) was stirred in methanol (6 mL, 0.1 mol) at room temperature ) at room temperature for 1 hour and concentrated. The residue was purified by reverse phase preparative HPLC to afford a white solid.

Provenance & Evidence