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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 418574생성일: 2026년 10월 25일

N1-(3-fluoro-4-(thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamide → N1-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamide

https://huagongshe.com/reaction/418574

반응식

참여 물질

역할이름HCID투입량
반응물N1-(3-fluoro-4-(thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamideHCID 45488043—
반응물3-Fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)benzenamineHCID 59424507—
생성물N1-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamideHCID 44565164—

반응 단계

Following the procedure described for compound 5a (example 1, step 5) but substituting amine 9 for compound 12, title compound 5c was obtained as a white solid (78% yield). MS (m/z): 502.0 (M+H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08093264B2
출처 데이터셋uspto-grants-2012_01
ORD IDord-40a56a0c3f2c4a72ad2decfc47ae1db6
출처 메모uspto-grants-2012_01