反应详情

A composition suitable for administration in vaginal suppository form 1a prepared by weighing 2 mg of finely divided polynucleotide medicinal substance into a tared container, adding 10 ml of 0.5% bupivacaine HCl in purified water, to make a total of 10 g, and dissolving or mixing depending on the solubility of the medicinal substance; 70 g of glycerin is added and mixed; 20 g of granular gelatin is then added and the composition heated carefully on a steam bath until the gelatin is dissolved. The melted mixture is poured into chilled molds to yield 20 vaginal suppositories of 6 grams each containing 100 mcg of polynucleotide medicinal substance in admixture with 2.5 mg bupivacaine.

1. dissolutiondissolving
2. additionmixing
3. additionmixed
4. addition20 g of granular gelatin is then added
5. temperaturethe composition heated carefully on a steam bath until the gelatin
6. dissolutionis dissolved
7. additionThe melted mixture is poured
8. temperatureinto chilled molds