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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 418660Generated: November 1, 2026

4-Fluoroaniline → 1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic Acid

https://huagongshe.com/reaction/418660

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluoroanilineHCID 9731—
Reactant1-(Phenylcarbamoyl)cyclopropanecarboxylic acidHCID 19096871—
Product1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic AcidHCID 2108153057%

Reaction Steps

Following the procedure described above for the compound 161 (scheme 45), but replacing aniline for 4-fluoroaniline, title compound 181 was obtained in 57% yield. MS (m/z): 224.0 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093264B2
Source datasetuspto-grants-2012_01
ORD IDord-27d6eef04c69462a9addcb35f64e745b
Source noteuspto-grants-2012_01