Sodium Iodide → HCID 66649247, compound

Participants

Reaction Conditions

Reaction Steps

To a flask containing a suspension of 419 (0.299 g, 0.753 mmol) in acetonitrile (8 mL) was added chlorotrimethylsilane (0.095 mL, 0.748 mmol) followed by sodium iodide (0.112 g, 0.748 mmol). The mixture was then heated to between 70 to 100° C. over 24 hours. Over this time four additional portions of chlorotrimethylsilane (0.095 mL each portion) and sodium iodide (0.112 g each portion) were added. The reaction mixture was then cooled to room temperature and the formed precipitate was collected by filtration, washed with NH4OH and water, and dried to provide title compound 420 as a brown solid (0.283 g, 98%). MS (m/z): 284.0 (M+H), 406.0 (M+Na).

Provenance & Evidence