4-Fluoroiodobenzene → 1-(4-Fluorophenyl)-1H-indazol-4-amine
Reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:16]2[CH:15]=[CH:14][CH:13]=[C:12]([NH2:17])[C:11]=2[CH:10]=[N:9]1.N1C2C=CC=C(N)C=2C=N1.[F:28]C1C=CC(I)=CC=1>>[F:28][C:6]1[CH:5]=[CH:4][C:3]([N:8]2[C:16]3[CH:15]=[CH:14][CH:13]=[C:12]([NH2:17])[C:11]=3[CH:10]=[N:9]2)=[CH:2][CH:7]=1Participants
4
Procedure
Similarly prepared to Intermediate 1 from 1H-indazol-4-amine and 4-fluoro-1-iodobenzene.
Sources & evidence
- ORD record
- ord-190412fe022444ae8d2c686537e587a2
- Source dataset
- uspto-grants-2012_01
- Patent number
- US08093281B2
Reaction notes
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