1-(4-Fluorophenyl)-1H-indazol-4-amine → 4-(2,3-Dihydro-1-benzofuran-7-yl)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-1h-indazol-4-yl]amino}methyl)-4-methyl-2-pentanol

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-(4-Fluorophenyl)-1H-indazol-4-amine	HCID 24938058	—
Edukt	7-[1,1-Dimethyl-2-(2-trifluoromethyloxiranyl)ethyl]-2,3-dihydrobenzofuran	HCID 57775518	—
Produkt	4-(2,3-Dihydro-1-benzofuran-7-yl)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-1h-indazol-4-yl]amino}methyl)-4-methyl-2-pentanol	HCID 57615943	—

Reaktionsschritte

Prepared similarly to Example 1 from racemic 7-{1,1-dimethyl-2-[2-(trifluoromethyl)-2-oxiranyl]ethyl}-2,3-dihydro-1-benzofuran (which may be prepared according to WO 04/063163) and 1-(4-fluorophenyl)-1H-indazol-4-amine (Intermediate 2).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08093281B2
Quelldatensatz	uspto-grants-2012_01
ORD ID	ord-c6d7c164a2f5465a8f961e9f7900a1cd
Quellennotiz	uspto-grants-2012_01