Water → HCID 86607742, compound

Participants

Reaction Steps

In a 50 mL round-bottomed flask fitted with condenser and magnetic stirrer were placed 2-(4-hydroxyphenyl)chromen-4-one (150 mg, 0.63 mmol), Ac2O (96 mg, 0.94 mmol), Et3N (96 mg, 0.94 mmol) and catalytic amount of DMAP in DCM (2 mL) and then the reaction mixture was stirred for 24 h at rt. The reaction mixture was poured into water and extracted with EtOAc. The organic layer washed with water, dried and concentrated to gave 160 mg of acetic acid 4-(4-oxo-4H-chromen-2-yl)phenyl acetate (91%). MS (ES) m/z: 281.15 (M+1), and 239.12.

Provenance & Evidence